Pesquisa | Biblioteca Virtual em Saúde

1.

Bedside Back to Bench: Building Bridges between Basic and Clinical Genomic Research.

Manolio, Teri A; Fowler, Douglas M; Starita, Lea M; Haendel, Melissa A; MacArthur, Daniel G; Biesecker, Leslie G; Worthey, Elizabeth; Chisholm, Rex L; Green, Eric D; Jacob, Howard J; McLeod, Howard L; Roden, Dan; Rodriguez, Laura Lyman; Williams, Marc S; Cooper, Gregory M; Cox, Nancy J; Herman, Gail E; Kingsmore, Stephen; Lo, Cecilia; Lutz, Cathleen; MacRae, Calum A; Nussbaum, Robert L; Ordovas, Jose M; Ramos, Erin M; Robinson, Peter N; Rubinstein, Wendy S; Seidman, Christine; Stranger, Barbara E; Wang, Haoyi; Westerfield, Monte; Bult, Carol.

Cell ; 169(1): 6-12, 2017 03 23.

Artigo em Inglês | MEDLINE | ID: mdl-28340351

2.

Dihydropyrimidine dehydrogenase gene variants for predicting grade 4-5 fluoropyrimidine-induced toxicity: FUSAFE individual patient data meta-analysis.

Le Teuff, Gwénaël; Cozic, Nathalie; Boyer, Jean-Christophe; Boige, Valérie; Diasio, Robert B; Taieb, Julien; Meulendijks, Didier; Palles, Claire; Schwab, Matthias; Deenen, Maarten; Largiadèr, Carlo R; Marinaki, Anthony; Jennings, Barbara A; Wettergren, Yvonne; Di Paolo, Antonello; Gross, Eva; Budai, Barna; Ackland, Stephen P; van Kuilenburg, André B P; McLeod, Howard L; Milano, Gérard; Thomas, Fabienne; Loriot, Marie-Anne; Kerr, David; Schellens, Jan H M; Laurent-Puig, Pierre; Shi, Qian; Pignon, Jean-Pierre; Etienne-Grimaldi, Marie-Christine.

Br J Cancer ; 130(5): 808-818, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38225422

3.

Pharmacogenetic and clinical risk factors for bevacizumab-related gastrointestinal hemorrhage in prostate cancer patients treated on CALGB 90401 (Alliance).

Patel, Jai N; Jiang, Chen; Owzar, Kouros; Hertz, Daniel L; Wang, Janey; Mulkey, Flora A; Kelly, William K; Halabi, Susan; Furukawa, Yoichi; Lassiter, Cameron; Dorsey, Susan G; Friedman, Paula N; Small, Eric J; Carducci, Michael A; Kelley, Michael J; Nakamura, Yusuke; Kubo, Michiaki; Ratain, Mark J; Morris, Michael J; McLeod, Howard L.

Pharmacogenomics J ; 24(2): 6, 2024 Mar 04.

Artigo em Inglês | MEDLINE | ID: mdl-38438359

4.

High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs.

Akhtari, Farida S; Green, Adrian J; Small, George W; Havener, Tammy M; House, John S; Roell, Kyle R; Reif, David M; McLeod, Howard L; Wiltshire, Timothy; Motsinger-Reif, Alison A.

PLoS Genet ; 17(8): e1009732, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34437536

5.

Biomarkers for Response to Anti-PD-1/Anti-PD-L1 Immune Checkpoint Inhibitors: A Large Meta-Analysis.

Mariam, Arshiya; Kamath, Suneel; Schveder, Kimberly; McLeod, Howard L; Rotroff, Daniel M.

Oncology (Williston Park) ; 37(5): 210-219, 2023 05 09.

Artigo em Inglês | MEDLINE | ID: mdl-37216635

6.

A two-stage genome-wide association study to identify novel genetic loci associated with acute radiotherapy toxicity in nasopharyngeal carcinoma.

Wang, Yang; Xiao, Fan; Zhao, Yi; Mao, Chen-Xue; Yu, Lu-Lu; Wang, Lei-Yun; Xiao, Qi; Liu, Rong; Li, Xi; McLeod, Howard L; Hu, Bi-Wen; Huang, Yu-Ling; Lv, Qiao-Li; Xie, Xiao-Xue; Huang, Wei-Hua; Zhang, Wei; Guo, Cheng-Xian; Li, Jin-Gao; Yin, Ji-Ye.

Mol Cancer ; 21(1): 169, 2022 08 23.

Artigo em Inglês | MEDLINE | ID: mdl-35999636

7.

Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients.

Quintanilha, Julia C F; Wang, Jin; Sibley, Alexander B; Jiang, Chen; Etheridge, Amy S; Shen, Fei; Jiang, Guanglong; Mulkey, Flora; Patel, Jai N; Hertz, Daniel L; Dees, Elizabeth Claire; McLeod, Howard L; Bertagnolli, Monica; Rugo, Hope; Kindler, Hedy L; Kelly, William Kevin; Ratain, Mark J; Kroetz, Deanna L; Owzar, Kouros; Schneider, Bryan P; Lin, Danyu; Innocenti, Federico.

Br J Cancer ; 126(2): 265-274, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34616010

8.

Race and smoking status associated with paclitaxel drug response in patient-derived lymphoblastoid cell lines.

Akhtari, Farida S; Havener, Tammy M; Hertz, Daniel L; Ash, Jeremy; Larson, Alexandra; Carey, Lisa A; McLeod, Howard L; Motsinger-Reif, Alison A.

Pharmacogenet Genomics ; 31(2): 48-52, 2021 02 01.

Artigo em Inglês | MEDLINE | ID: mdl-32941389

9.

Pharmacogenetic study in gastric cancer patients treated with adjuvant fluorouracil/leucovorin or epirubicin/cisplatin/fluorouracil before and after chemoradiation on CALGB 80101 (Alliance).

Patel, Jai N; Jiang, Chen; Owzar, Kouros; Mulkey, Flora; Luzum, Jasmine A; Mamon, Harvey J; Haller, Daniel G; Dragovich, Tomislav; Alberts, Steven R; Bjarnason, Georg; Willet, Christopher G; Niedzwiecki, Donna; Enzinger, Peter; Ratain, Mark J; Fuchs, Charles; McLeod, Howard L.

Pharmacogenet Genomics ; 31(9): 215-220, 2021 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-34149004

10.

Pharmacogenomics.

Roden, Dan M; McLeod, Howard L; Relling, Mary V; Williams, Marc S; Mensah, George A; Peterson, Josh F; Van Driest, Sara L.

Lancet ; 394(10197): 521-532, 2019 08 10.

Artigo em Inglês | MEDLINE | ID: mdl-31395440

11.

Opportunities, resources, and techniques for implementing genomics in clinical care.

Manolio, Teri A; Rowley, Robb; Williams, Marc S; Roden, Dan; Ginsburg, Geoffrey S; Bult, Carol; Chisholm, Rex L; Deverka, Patricia A; McLeod, Howard L; Mensah, George A; Relling, Mary V; Rodriguez, Laura Lyman; Tamburro, Cecelia; Green, Eric D.

Lancet ; 394(10197): 511-520, 2019 Aug 10.

Artigo em Inglês | MEDLINE | ID: mdl-31395439

12.

An initial genetic analysis of gemcitabine-induced high-grade neutropenia in pancreatic cancer patients in CALGB 80303 (Alliance).

Innocenti, Federico; Jiang, Chen; Sibley, Alexander B; Denning, Stefanie; Etheridge, Amy S; Watson, Dorothy; Niedzwiecki, Donna; Hatch, Ace J; Hurwitz, Herbert I; Nixon, Andrew B; Furukawa, Yoichi; Kubo, Michiaki; Crona, Daniel J; Kindler, Hedy L; McLeod, Howard L; Ratain, Mark J; Owzar, Kouros.

Pharmacogenet Genomics ; 29(6): 123-131, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-30889042

13.

Influence of genetic variation in the vitamin D pathway on plasma 25-hydroxyvitamin D₃ levels and survival among patients with metastatic colorectal cancer.

Yuan, Chen; Renfro, Lindsay; Ambadwar, Pratibha B; Ou, Fang-Shu; McLeod, Howard L; Innocenti, Federico; Meyerhardt, Jeffrey A; Wolpin, Brian M; Goldberg, Richard M; Grothey, Axel; Fuchs, Charles S; Ng, Kimmie.

Cancer Causes Control ; 30(7): 757-765, 2019 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-31104167

14.

When will clinical trials finally reflect diversity?

Knepper, Todd C; McLeod, Howard L.

Nature ; 557(7704): 157-159, 2018 05.

Artigo em Inglês | MEDLINE | ID: mdl-29743700

15.

Adherence to Adjuvant Imatinib Therapy in Patients with Gastrointestinal Stromal Tumor in Clinical Practice: A Cross-Sectional Study.

Wang, Yirong; Zhang, Peng; Han, Yong; Nelson, Ryan S; McLeod, Howard L; Tao, Kaixiong; Yuan, Yonghua; Zhang, Min; Xiang, Hongping; Zhou, Hong.

Chemotherapy ; 64(4): 197-204, 2019.

Artigo em Inglês | MEDLINE | ID: mdl-31955170

16.

Value of Supportive Care Pharmacogenomics in Oncology Practice.

Patel, Jai N; Wiebe, Lauren A; Dunnenberger, Henry M; McLeod, Howard L.

Oncologist ; 23(8): 956-964, 2018 08.

Artigo em Inglês | MEDLINE | ID: mdl-29622698

17.

Prediction of chemotherapy-induced nausea and vomiting from patient-reported and genetic risk factors.

Puri, Sonam; Hyland, Kelly A; Weiss, Kristine Crowe; Bell, Gillian C; Gray, Jhanelle E; Kim, Richard; Lin, Hui-Yi; Hoogland, Aasha I; Gonzalez, Brian D; Nelson, Ashley M; Kinney, Anita Y; Fischer, Stacy M; Li, Daneng; Jacobsen, Paul B; McLeod, Howard L; Jim, Heather S L.

Support Care Cancer ; 26(8): 2911-2918, 2018 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-29546524

18.

Clonal haemopoiesis and therapy-related myeloid malignancies in elderly patients: a proof-of-concept, case-control study.

Gillis, Nancy K; Ball, Markus; Zhang, Qing; Ma, Zhenjun; Zhao, YuLong; Yoder, Sean J; Balasis, Maria E; Mesa, Tania E; Sallman, David A; Lancet, Jeffrey E; Komrokji, Rami S; List, Alan F; McLeod, Howard L; Alsina, Melissa; Baz, Rachid; Shain, Kenneth H; Rollison, Dana E; Padron, Eric.

Lancet Oncol ; 18(1): 112-121, 2017 01.

Artigo em Inglês | MEDLINE | ID: mdl-27927582

19.

Correction: Bevacizumab-induced hypertension and proteinuria: a genome-wide study of more than 1000 patients.

Quintanilha, Julia C F; Wang, Jin; Sibley, Alexander B; Jiang, Chen; Etheridge, Amy S; Shen, Fei; Jiang, Guanglong; Mulkey, Flora; Patel, Jai N; Hertz, Daniel L; Dees, Elizabeth Claire; McLeod, Howard L; Bertagnolli, Monica; Rugo, Hope; Kindler, Hedy L; Kelly, William Kevin; Ratain, Mark J; Kroetz, Deanna L; Owzar, Kouros; Schneider, Bryan P; Lin, Danyu; Innocenti, Federico.

Br J Cancer ; 126(1): 162, 2022 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-34853435

20.

Comprehensive assessment of cytochromes P450 and transporter genetics with endoxifen concentration during tamoxifen treatment.

Marcath, Lauren A; Deal, Allison M; Van Wieren, Emily; Danko, William; Walko, Christine M; Ibrahim, Joseph G; Weck, Karen E; Jones, David R; Desta, Zeruesenay; McLeod, Howard L; Carey, Lisa A; Irvin, William J; Hertz, Daniel L.

Pharmacogenet Genomics ; 27(11): 402-409, 2017 11.

Artigo em Inglês | MEDLINE | ID: mdl-28877533

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